ea0029p40 | Adrenal cortex | ICEECE2012
Rubin B.
, Pezzani R.
, Barollo S.
, Mariniello B.
, Salva M.
, Iacobone M.
, Fassina A.
, Mantero F.
Adrenocortical tumors (ACT) include benign and malignant tumors. Adrenocortical carcinomas (ACC) are highly malignant neoplasms with a poor prognosis, but their genetic alterations to date identified are limited. Laboratory studies on ACT have revealed a wide variety of signaling pathways involved in these tumors, among these Wnt/β-catenin signaling pathway and Ras/Raf/MEK/ERK pathway resulted often disregulated. Another important factor in many signaling pathways is the ...